Opipramol (dihydrochloride)
Opipramol (Ensidon) is an atypical tricyclic antidepressant (TCA) . Opipramol acts primarily as a sigma (σ) receptor agonist and can potently interact with sigma recognition sites with a Ki value of 50 nM. Opipramol can be used for the research of generalized anxiety disorder (GAD) [1][2].
Product Specifications
CAS Number
909-39-7
Product Name Alternative
Ensidon (dihydrochloride) ; G-33040 (dihydrochloride)
UNSPSC
12352005
Hazard Statement
H302-H410
Target
Sigma Receptor
Related Pathways
Neuronal Signaling
Field of Research
Neurological Disease
Smiles
OCCN1CCN(CCCN2C3=CC=CC=C3C=CC4=CC=CC=C42)CC1.Cl.Cl
Molecular Formula
C23H31Cl2N3O
Molecular Weight
436.42
Precautions
P264-P270-P273-P330-P391-P501
References & Citations
[1]Möller HJ, et al. Opipramol for the treatment of generalized anxiety disorder: a placebo-controlled trial including an alprazolam-treated group. J Clin Psychopharmacol. 2001 Feb;21 (1) :59-65. |[2]Rao TS, et al. Neurochemical characterization of dopaminergic effects of opipramol, a potent sigma receptor ligand, in vivo. Neuropharmacology. 1990 Dec;29 (12) :1191-7.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 3
Available Sizes
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