12-Oxo phytodienoic acid (≥90%)
12-Oxo phytodienoic acid (≥90%) (12-OPDA (≥90%) ) is a plant lipid-derived anti-inflammatory compound. 12-Oxo phytodienoic acid (≥90%) suppresses neuroinflammation by inhibiting Nf-κB and p38 MAPK signaling in Lipopolysaccharides (LPS) -activated cells. 12-Oxo phytodienoic acid (≥90%) can be used for neurodegenerative diseases research[1].
Product Specifications
CAS Number
85551-10-6
Product Name Alternative
12-OPDA (≥90%)
UNSPSC
12352211
Target
NF-κB; p38 MAPK
Related Pathways
MAPK/ERK Pathway; NF-κB
Field of Research
Inflammation/Immunology; Neurological Disease
Concentration
3.42 mM * 1 mL in Ethanol
Purity
92.2
Smiles
O=C(O)CCCCCCC[C@H]1C=CC([C@H]1C/C=C\CC)=O
Molecular Formula
C18H28O3
Molecular Weight
292.41
References & Citations
[1]Taki-Nakano N, et al. 12-oxo-phytodienoic acid, a plant-derived oxylipin, attenuates lipopolysaccharide-induced inflammation in microglia. Biochem Biophys Res Commun. 2016 May 13;473 (4) :1288-1294.
Shipping Conditions
Blue Ice
Storage Conditions
Solution, -20°C, protect from light, 2 years
Scientific Category
Natural Products
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC880460-500 1x 500 µL
CD44 Standard (156-3C11), CF488A conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC470030-500 1x 500 µL
Insulin (2D11-H5), CF647 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC940012-500 1x 500 µL
Tyrosinase (T311), CF594 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC680181-100 1x 100 µL
CD59 (heavy chain of Protectin) (BRA-10G), CF568 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC041203-100 1x 100 µL
Smooth Muscle Actin (ACTA2/791 +1A4), CF405S conjugate, 0.1mg/mL
Sign In for Pricing
View Details