Anhydrotetracycline (hydrochloride)

Anhydrotetracycline hydrochloride, a tetracycline biosynthetic precursor, is a potent competitive broad-spectrum tetracycline destructase enzymes inhibitor. Anhydrotetracycline hydrochloride is an effector for tetracycline controlled gene expression systems in eukaryotic cells[1].

Product Specifications

CAS Number

[13803-65-1]

UNSPSC

12352005

Hazard Statement

H319, H361

Target

Antibiotic; Bacterial

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Concentration

10mM

Purity

99.68

Solubility

DMSO : 100 mg/mL (ultrasonic) |H2O : 170 mg/mL (ultrasonic)

Smiles

O=C(C(C1=O)=C(O)[C@@H](N(C)C)[C@]2([H])CC3=C(C([C@@]21O)=O)C(O)=C4C(O)=CC=CC4=C3C)N.[H]Cl

Molecular Formula

C22H23ClN2O7

Molecular Weight

462.88

Precautions

H319, H361

References & Citations

[1]Jana L Markley, et al. Semisynthetic Analogues of Anhydrotetracycline as Inhibitors of Tetracycline Destructase Enzymes. ACS Infect Dis. 2019 Apr 12;5 (4) :618-633.