BMS 182874 (Standard)
BMS 182874 (Standard) is the analytical standard of BMS 182874. This product is intended for research and analytical applications. BMS 182874 is an orallyactive, highly selective endothelin receptor (ETA receptor) antagonist, with IC50 value of 0.150 μM, Ki of 0.055 μM. BMS 182874 reduces the arterial pressure of Deoxycorticosterone acetate induced hypertension model in rats, and can be used for cardiovascular disease research[1].
Product Specifications
CAS Number
153042-42-3
UNSPSC
12352100
Target
Endothelin Receptor; Reference Standards
Related Pathways
GPCR/G Protein; Others
Field of Research
Metabolic Disease; Cardiovascular Disease
Smiles
O=S(C1=C2C=CC=C(C2=CC=C1)N(C)C)(NC3=C(C(C)=NO3)C)=O
Molecular Formula
C17H19N3O3S
Molecular Weight
345.42
References & Citations
[1]Abdullaha M, et.al. Methoxy-naphthyl-Linked N-Benzyl Pyridinium Styryls as Dual Cholinesterase Inhibitors: Design, Synthesis, Biological Evaluation, and Structure-Activity Relationship. ACS Omega. 2023 May 9;8 (20) :17591-17608.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
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