CGS 24012

CGS 24012 (DPMA) is a selective adenosine A2 agonist. CGS 24012 produces significant increases in cardiac output. CGS 24012 reduces renal vascular resistance to the greatest extent and produces a concomitant significant increase in renal blood flow. CGS 24012 can be used in the research of hypertension[1].

Product Specifications

CAS Number

[120442-40-2]

Product Name Alternative

DPMA; PD 125944

UNSPSC

12352005

Target

Adenosine Receptor

Related Pathways

GPCR/G Protein

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Smiles

N(CC(C1=CC(OC)=CC(OC)=C1)C2=C(C)C=CC=C2)C3=C4C(N(C=N4)[C@@H]5O[C@H](CO)[C@@H](O)[C@H]5O)=NC=N3

Molecular Formula

C27H31N5O6

Molecular Weight

521.57

References & Citations

[1]Webb RL, et al. Cardiovascular effects of adenosine A2 agonists in the conscious spontaneously hypertensive rat: a comparative study of three structurally distinct ligands. J Pharmacol Exp Ther. 1991 Dec;259 (3) :1203-12.