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AG-1801

AG-1801, a nitrobenzopyridine derivative, is a tyrosine phosphorylation inhibitor. AG-1801 can induce the disintegration of the microtubule network in living cells, and does not inhibit microtubule polymerization in vitro. AG-1801 can be used for the study of microtubule-related signaling pathways[1].

Product Specifications

CAS Number

204010-55-9

UNSPSC

12352005

Target

Endogenous Metabolite

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Others

Smiles

O=C(/C(C#N)=C/C1=CC=C(C=C1)[N+]([O-])=O)NCC2=CC=CC=C2

Molecular Formula

C17H13N3O3

Molecular Weight

307.30

References & Citations

[1]Volberg T, et al. Disruption of microtubules in living cells by tyrphostin AG-1714. Cell Motil Cytoskeleton. 2000 Mar;45 (3) :223-34.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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