AG-1801
AG-1801, a nitrobenzopyridine derivative, is a tyrosine phosphorylation inhibitor. AG-1801 can induce the disintegration of the microtubule network in living cells, and does not inhibit microtubule polymerization in vitro. AG-1801 can be used for the study of microtubule-related signaling pathways[1].
Product Specifications
CAS Number
[204010-55-9]
UNSPSC
12352005
Target
Endogenous Metabolite
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Others
Smiles
O=C(/C(C#N)=C/C1=CC=C(C=C1)[N+]([O-])=O)NCC2=CC=CC=C2
Molecular Formula
C17H13N3O3
Molecular Weight
307.30
References & Citations
[1]Volberg T, et al. Disruption of microtubules in living cells by tyrphostin AG-1714. Cell Motil Cytoskeleton. 2000 Mar;45 (3) :223-34.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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