Abanoquil (methylsulfate)
Abanoquil methylsulfate (UK-52046 methylsulfate) is an alpha-1 family adrenergic receptor antagonist. Abanoquil methylsulfate can be used in research on cardiovascular diseases such as arrhythmias and erectile dysfunction[1][2].
Product Specifications
CAS Number
[118931-00-3]
Product Name Alternative
UK-52046 (methylsulfate)
UNSPSC
12352005
Target
Adrenergic Receptor
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Smiles
COC1=C(C=C2C(N)=CC(N3CC4=C(CC3)C=C(C(OC)=C4)OC)=NC2=C1)OC.O=S(C)(O)=O
Molecular Formula
C23H29N3O7S
Molecular Weight
491.56
References & Citations
[1]Giraldi A, et al. Abanoquil, a new alpha-1 adrenoceptor antagonist. In vitro and in vivo effect on erectile tissue. Int J Impot Res. 2000 Mar;12 Suppl 1:S37-40. |[2]Tham TC, et al. Dose-dependent alpha 1-adrenoceptor antagonist activity of the anti-arrhythmic drug, abanoquil (UK-52,046), without reduction in blood pressure in man. Br J Clin Pharmacol. 1992 Apr;33 (4) :405-9.
Shipping Conditions
Room temperature
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-118039/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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