Abanoquil (methylsulfate)

Abanoquil methylsulfate (UK-52046 methylsulfate) is an alpha-1 family adrenergic receptor antagonist. Abanoquil methylsulfate can be used in research on cardiovascular diseases such as arrhythmias and erectile dysfunction[1][2].

Product Specifications

CAS Number

[118931-00-3]

Product Name Alternative

UK-52046 (methylsulfate)

UNSPSC

12352005

Target

Adrenergic Receptor

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Smiles

COC1=C(C=C2C(N)=CC(N3CC4=C(CC3)C=C(C(OC)=C4)OC)=NC2=C1)OC.O=S(C)(O)=O

Molecular Formula

C23H29N3O7S

Molecular Weight

491.56

References & Citations

[1]Giraldi A, et al. Abanoquil, a new alpha-1 adrenoceptor antagonist. In vitro and in vivo effect on erectile tissue. Int J Impot Res. 2000 Mar;12 Suppl 1:S37-40. |[2]Tham TC, et al. Dose-dependent alpha 1-adrenoceptor antagonist activity of the anti-arrhythmic drug, abanoquil (UK-52,046), without reduction in blood pressure in man. Br J Clin Pharmacol. 1992 Apr;33 (4) :405-9.