CC-3052

CC-3052 is a phosphodiesterase 4 (PDE4) inhibitor with immunomodulatory activities. CC-3052 reduces neutrophil apoptosis in HIV⁺. CC-3052 is promising for research of HIV-related diseases[1].

Product Specifications

CAS Number

216884-02-5

UNSPSC

12352005

Target

Apoptosis; HIV; Phosphodiesterase (PDE)

Related Pathways

Anti-infection; Apoptosis; Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Infection

Smiles

O=C(CC(N1C(C2=C(C1)C=CC=C2)=O)C3=CC=C(C(OC)=C3)OC)OC

Molecular Formula

C20H21NO5

Molecular Weight

355.38

References & Citations

[1]Guckian M, et al. Thalidomide analogue CC-3052 reduces HIV+ neutrophil apoptosis in vitro[J]. Clinical & Experimental Immunology, 2000, 121 (3) : 472-479.