Y-05460M-A

Y-05460M-A is a substituted isocoumarin antibiotic. Y-05460M-A exhibits inhibitory activity against Gram-positive and Gram-negative bacteria. Y-05460M-A is cytotoxic against P388 lymphatic leukemia. Y-05460M-A also has antiulcer activity. Y-05460M-A is a one-carbon lower homologue of PM-04128. Y-05460M-A can be achieved from N-Boc-L-valine[1][2].

Product Specifications

CAS Number

126262-07-5

UNSPSC

12352005

Target

Antibiotic

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Smiles

O=C1C2=C(O)C=CC=C2C[C@]([C@H](CC(C)C)NC([C@@H](O)[C@@H](O)[C@@H](N)C(C)C)=O)([H])O1

Molecular Formula

C21H32N2O6

Molecular Weight

408.49

References & Citations

[1]Sato, T., et al., (1992) . A new isocoumarin antibiotic, Y-05460M-A. The Journal of antibiotics, 45 (12), 1949-1952. |[2]Enomoto, M., & Kuwahara, S. (2009) . Concise synthesis of PM-94128 and Y-05460M-A. The Journal of organic chemistry, 74 (19), 7566-7569.