Y-05460M-A
Y-05460M-A is a substituted isocoumarin antibiotic. Y-05460M-A exhibits inhibitory activity against Gram-positive and Gram-negative bacteria. Y-05460M-A is cytotoxic against P388 lymphatic leukemia. Y-05460M-A also has antiulcer activity. Y-05460M-A is a one-carbon lower homologue of PM-04128. Y-05460M-A can be achieved from N-Boc-L-valine[1][2].
Product Specifications
CAS Number
126262-07-5
UNSPSC
12352005
Target
Antibiotic
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Smiles
O=C1C2=C(O)C=CC=C2C[C@]([C@H](CC(C)C)NC([C@@H](O)[C@@H](O)[C@@H](N)C(C)C)=O)([H])O1
Molecular Formula
C21H32N2O6
Molecular Weight
408.49
References & Citations
[1]Sato, T., et al., (1992) . A new isocoumarin antibiotic, Y-05460M-A. The Journal of antibiotics, 45 (12), 1949-1952. |[2]Enomoto, M., & Kuwahara, S. (2009) . Concise synthesis of PM-94128 and Y-05460M-A. The Journal of organic chemistry, 74 (19), 7566-7569.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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