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CGP-75355

CGP-75355 is an inhibitor of HIV-1 protease with IC50 of 26 nM. CGP-75355 is a bis (L-tert-leucine) derivative[1][2].

Product Specifications

CAS Number

191594-64-6

UNSPSC

12352005

Target

HIV; HIV Protease

Related Pathways

Anti-infection; Metabolic Enzyme/Protease

Applications

COVID-19-anti-virus

Field of Research

Infection

Smiles

CC(C)(C)[C@@H](C(N[C@@H](CC1=CC=CC=C1)[C@@H](O)CN(NC([C@H](C(C)(C)C)NC(OC)=O)=O)CC2=CC=C(C3=CC=CC=C3)C=C2)=O)NC(OC)=O

Molecular Formula

C39H53N5O7

Molecular Weight

703.87

References & Citations

[1]Bold, G., et al., (1998) . New aza-dipeptide analogues as potent and orally absorbed HIV-1 protease inhibitors: candidates for clinical development. Journal of medicinal chemistry, 41 (18), 3387-3401.|[2]Wieslaw M. Kazmierski, (2011) . Antiviral Drugs: From Basic Discovery Through Clinical Trials.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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