CGP-75355
CGP-75355 is an inhibitor of HIV-1 protease with IC50 of 26 nM. CGP-75355 is a bis (L-tert-leucine) derivative[1][2].
Product Specifications
CAS Number
[191594-64-6]
UNSPSC
12352005
Target
HIV; HIV Protease
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Applications
COVID-19-anti-virus
Field of Research
Infection
Smiles
CC(C)(C)[C@@H](C(N[C@@H](CC1=CC=CC=C1)[C@@H](O)CN(NC([C@H](C(C)(C)C)NC(OC)=O)=O)CC2=CC=C(C3=CC=CC=C3)C=C2)=O)NC(OC)=O
Molecular Formula
C39H53N5O7
Molecular Weight
703.87
References & Citations
[1]Bold, G., et al., (1998) . New aza-dipeptide analogues as potent and orally absorbed HIV-1 protease inhibitors: candidates for clinical development. Journal of medicinal chemistry, 41 (18), 3387-3401.|[2]Wieslaw M. Kazmierski, (2011) . Antiviral Drugs: From Basic Discovery Through Clinical Trials.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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