PenCB (Standard)

PenCB (Standard) is the analytical standard of PenCB. This product is intended for research and analytical applications. PenCB (PCB 118) could induces pyroptosis by priming and activating NFκB-dependent NLRP3 inflammasome. PCB 118 induces oxidative stress and pyroptosis are dependent on Aryl hydrocarbon receptor (AhR) activation and subsequent cytochrome P450 1A1 upregulation[1].

Product Specifications

CAS Number

[31508-00-6]

UNSPSC

12352100

Target

Pyroptosis; Reference Standards

Related Pathways

Apoptosis; Immunology/Inflammation; Others

Field of Research

Cancer

Smiles

ClC1=C(C=C(C(C2=CC=C(C(Cl)=C2)Cl)=C1)Cl)Cl

Molecular Formula

C12H5Cl5

Molecular Weight

326.44

References & Citations

[1]Yang Long, et al. ROS-induced NLRP3 inflammasome priming and activation mediate PCB 118- induced pyroptosis in endothelial cells. Ecotoxicol Environ Saf. 2020 Feb:189:109937.