FE-999024
FE-999024 (CH-2856) is a specific tissue kallikrein inhibitor. FE-999024 can inhibit cancer cells invasion with a maximum of 39%. FE-999024 can reduce eosinophilia in a model of allergic inflammation. FE-999024 can be used for the researches of cancer, inflammation and immunology[1][2].
Product Specifications
CAS Number
[168825-65-8]
Product Name Alternative
CH-2856
UNSPSC
12352005
Target
Kallikrein
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Smiles
O=C(N)[C@H](CC1=C2C=CC=CC2=CC=C1)N(C([C@@H](CC3=CC=C(Cl)C=C3)N)=O)CCCNC(N)=N
Molecular Formula
C26H31ClN6O2
Molecular Weight
495.02
References & Citations
[1]Wolf WC, et al. A synthetic tissue kallikrein inhibitor suppresses cancer cell invasiveness. Am J Pathol. 2001 Nov;159 (5) :1797-805.|[2]Evans DM, et al. Synthetic inhibitors of human tissue kallikrein. Immunopharmacology. 1996 May;32 (1-3) :117-8.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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