Ronopterin

Ronopterin (VAS203) is a NO Synthase inhibitor. Ronopterin can be used in research on diseases of the urogenital system and the nervous system[1][2].

Product Specifications

CAS Number

[206885-38-3]

Product Name Alternative

VAS203

UNSPSC

12352005

Target

NO Synthase

Related Pathways

Immunology/Inflammation

Field of Research

Metabolic Disease; Neurological Disease

Smiles

C[C@H](O)[C@@H](C1NC2=C(N)N=C(N)N=C2NC1)O

Molecular Formula

C9H16N6O2

Molecular Weight

240.26

References & Citations

[1]Ott C, et al. Effects of the nitric oxide synthase inhibitor ronopterin (VAS203) on renal function in healthy volunteers. Br J Clin Pharmacol. 2019 May;85 (5) :900-907.|[2]Tegtmeier F, et al. Efficacy of Ronopterin (VAS203) in Patients with Moderate and Severe Traumatic Brain Injury (NOSTRA phase III trial) : study protocol of a confirmatory, placebo-controlled, randomised, double blind, multi-centre study. Trials. 2020 Jan 14;21 (1) :80.