GW 275175X
GW 275175X is an inhibitor of the terminase complex involved in cleavage and packaging of the unit length DNA into the capsids. GW 275175X exhibits long plasma half-life. GW 275175X is a BDCRB derivative. GW 275175X exhibits anti-HCMV activity through inhibiting maturation of viral DNA[1][2][3].
Product Specifications
CAS Number
217950-62-4
UNSPSC
12352005
Target
CMV
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Smiles
O[C@H]1[C@H](N2C3=CC(Cl)=C(Cl)C=C3N=C2Br)OC[C@@H](O)[C@H]1O
Molecular Formula
C12H11BrCl2N2O4
Molecular Weight
398.04
References & Citations
[1]Emery, V. C., & Hassan-Walker, A. F. (2002) . Focus on new drugs in development against human cytomegalovirus. Drugs, 62 (13), 1853-1858.|[2]Williams, S. L., et al., (2003) . In vitro activities of benzimidazole D- and L-ribonucleosides against herpesviruses. Antimicrobial agents and chemotherapy, 47 (7), 2186-2192.|[3]McGregor, A., & Choi, K. Y. (2011) . Cytomegalovirus antivirals and development of improved animal models. Expert opinion on drug metabolism & toxicology, 7 (10), 1245-1265.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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