Clogestone acetate

Clogestone acetate (AY-11440) is an orally active progesterone receptor agonist. Clogestone acetate reduces adrenal and ovarian weight, as well as serum and adrenocortical ketone levels in rats[1][2].

Product Specifications

CAS Number

[3044-32-4]

Product Name Alternative

AY-11440

UNSPSC

12352211

Target

Progesterone Receptor

Related Pathways

Vitamin D Related/Nuclear Receptor

Field of Research

Others

Smiles

CC([C@]1(CC[C@]2([C@@]3(C=C(C4=C[C@H](CC[C@@]4([C@]3(CC[C@]12C)[H])C)OC(C)=O)Cl)[H])[H])OC(C)=O)=O

Molecular Formula

C25H33ClO5

Molecular Weight

448.98

References & Citations

[1]Givner ML, et al. Effect of synthetic progestogens and estradiol-17 on adrenal function in the rat. Endocrinology. 1972 May;90 (5) :1238-44. |[2]Hinselmann M, et al. Klinische Untersuchungen mit dem neuartigen Gestagen Clogestonacetat [Clogestone acetate, a new orally effective progestagen]. Arch Gynakol. 1970 Aug 31;209 (2) :136-48. German.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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