MeV-IN-1

MeV-IN-1 (OX-1) is an inhibitor of specific specific Measles virus (MeV) entry with an IC50 of 100 M. MeV-IN-1 has an IC50 of 55 M against live MeV-Edm. MeV-IN-1 efficiently suppresses the formation of infectious centers. MeV-IN-1 exhibits negligible cytotoxicity. MeV-IN-1 potently suppresses R18 redistribution in MV-H- and MV-F-expressing cells, preventing membrane merging[1].

Product Specifications

CAS Number

[313527-44-5]

Product Name Alternative

OX-1

UNSPSC

12352005

Hazard Statement

H315-H319-H320

Target

Others

Related Pathways

Others

Applications

COVID-19-anti-virus

Field of Research

Infection

Smiles

NC1=CC=C(OC(CC2=CC=CC=C2)=N3)C3=C1

Molecular Formula

C14H12N2O

Molecular Weight

224.26

Precautions

P264-P280-P302+P352-P305+P351+P338-P362

References & Citations

[1]Plemper, R. K. et al., (2004) . A target site for template-based design of measles virus entry inhibitors. Proceedings of the National Academy of Sciences of the United States of America, 101 (15), 5628-5633.