BE-31405

BE-31405 is an antifungal antibiotic. BE-31405 can be isolated from the culture broth of the fungal strains such as Penicillium minioluteum F31405, Talaromyces siamensis FKA-61, and Phomopsis sp. FKA-62. BE-31405 exhibits potent growth inhibitory activity against pathogenic fungal strains including Candida albicans, Candida glabrata, and Cryptococcus neoformans. BE-31405 shows no cytotoxicity against mammalian cells[1][2].

Product Specifications

CAS Number

[158054-02-5]

UNSPSC

12352005

Target

Antibiotic; Fungal

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Smiles

O=C([C@]12C(C(C)C)=C[C@]3([H])[C@@]1(CO[C@]4(C5O)O[C@]6([H])[C@](O[C@@]5([H])[C@H]6OC(C)=O)([H])O4)C[C@]7([H])[C@H](C)CC[C@@]7([H])[C@@]2(C=O)C3)O

Molecular Formula

C28H36O10

Molecular Weight

532.58

References & Citations

[1]Okada, H., et al., (1998) . BE-31405, a new antifungal antibiotic produced by Penicillium minioluteum. I. Description of producing organism, fermentation, isolation, physico-chemical and biological properties. The Journal of antibiotics, 51 (12), 1081-1086. |[2]Nonaka, K., et al., (2015) . Induced production of BE-31405 by co-culturing of Talaromyces siamensis FKA-61 with a variety of fungal strains. The Journal of antibiotics, 68 (9), 573-578.