BMS-210285
BMS-210285 is a highly selective agonist for the 3 receptor. BMS-210285 has a Ki of 9 nM at the human 3-adrenoceptor. BMS-210285 possesses a 3 intrinsic activity of 83% relative to isoproterenol. BMS-210285 can be studied for obesity and type 2 diabetes research[1][2].
Product Specifications
CAS Number
344607-69-8
UNSPSC
12352005
Target
Adrenergic Receptor
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Smiles
CS(=O)(NC1=CC([C@@H](O)CN[C@@H](C2=CC=C(OC(F)F)C=C2)CC3=CC=CC(Cl)=C3)=CC=C1O)=O
Molecular Formula
C24H25ClF2N2O5S
Molecular Weight
526.98
References & Citations
[1]Hu, B., & Jennings, L. L. (2003) . Orally bioavailable beta 3-adrenergic receptor agonists as potential therapeutic agents for obesity and type-II diabetes. Progress in medicinal chemistry, 41, 167-194.|[2]Kordik, C. P., & Reitz, A. B. (1999) . Pharmacological treatment of obesity: therapeutic strategies. Journal of medicinal chemistry, 42 (2), 181-201.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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