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BI-44847

BI-44847 is a selective and orally active SGLT2 inhibitor. BI-44847 can increase UGE and decrease HbA1c levels. BI-44847 shows improvement in fasting and fed glucose levels. BI-44847 can be studied in research on type 2 diabetes mellitus (T2DM) [1].

Product Specifications

CAS Number

[421592-30-5]

UNSPSC

12352005

Target

SGLT

Related Pathways

Membrane Transporter/Ion Channel

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Smiles

O[C@H]([C@H]([C@@H]([C@@H](CO)O1)O)O)[C@H]1OC2=NN(C(C)C)C(C)=C2CC3=CC=C(OC)C=C3F

Molecular Formula

C21H29FN2O7

Molecular Weight

440.46

References & Citations

[1]Malla, P., et al. (2014) . Ramping glucosuria for management of type 2 diabetes mellitus: an emerging cynosure. Medicinal research reviews, 34 (6), 1146-1167.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

Phase 1

Curated Selection

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