NSC-57969
NSC-57969 is a multidrug resistant (MDR) -selective agent, exhibiting a robust Pgp-dependent toxic activity across diverse cancer cell lines[1].
Product Specifications
CAS Number
[6632-09-3]
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
P-glycoprotein
Related Pathways
Membrane Transporter/Ion Channel
Field of Research
Cancer
Smiles
OC1=C2N=CC=CC2=CC=C1CN3CCCCC3
Molecular Formula
C15H18N2O
Molecular Weight
242.32
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]András Füredi, et al. Identification and Validation of Compounds Selectively Killing Resistant Cancer: Delineating Cell Line-Specific Effects from P-Glycoprotein-Induced Toxicity. Mol Cancer Ther. 2017 Jan;16 (1) :45-56.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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