LY117018 (Standard)

LY117018 (Standard) is the analytical standard of LY117018. This product is intended for research and analytical applications. LY117018, a Raloxifene analog, is a selective estrogen receptor modulator. LY117018 exerts antiproliferative effects on breast cancer cell lines[1][2].

Product Specifications

CAS Number

[63676-25-5]

UNSPSC

12352100

Target

Estrogen Receptor/ERR; Reference Standards

Related Pathways

Others; Vitamin D Related/Nuclear Receptor

Field of Research

Cancer

Smiles

O=C(C1=CC=C(C=C1)OCCN2CCCC2)C3=C(SC4=CC(O)=CC=C43)C5=CC=C(C=C5)O

Molecular Formula

C27H25NO4S

Molecular Weight

459.56

References & Citations

[1]Dinda S, et al. Effects of LY117018 (a SERM analog of raloxifene) on tumor suppressor proteins and proliferation of breast cancer cells.Horm Mol Biol Clin Investig. 2010 Aug 1;2 (1) :211-7.|[2]Baumann KH, et al. Effects of celecoxib and ly117018 combination on human breast cancer cells in vitro.Breast Cancer (Auckl) . 2009 Apr 7;3:23-34.|[3]Yu J, et al.Raloxifene analogue LY117018 suppresses oxidative stress-induced endothelial cell apoptosis through activation of ERK1/2 signaling pathway.Eur J Pharmacol. 2008 Jul 28;589 (1-3) :32-6.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards