P38α inhibitor 7
P38α inhibitor 7 (compound 1) is an effective p38α inhibitor with oral efficacy and generally favorable pharmacokinetic properties[1].
Product Specifications
CAS Number
[668981-02-0]
UNSPSC
12352005
Target
P38 MAPK
Related Pathways
MAPK/ERK Pathway
Field of Research
Inflammation/Immunology
Smiles
FC1=CC(C2=C(C3=CN4C(C(C)C)=NN=C4C=C3)OC=N2)=C(F)C=C1
Molecular Formula
C18H14F2N4O
Molecular Weight
340.33
References & Citations
[1]Amit S. Kalgutkar, et al. Preclinical Pharmacokinetics and Metabolism of 6- (4- (2,5- Difluorophenyl) oxazol-5-yl) -3-isopropyl-[1,2,4]-triazolo[4,3-a] pyridine, a Novel and Selective p38a Inhibitor: Identification of an Active Metabolite in Preclinical Species and Human Liver Microsomes. Biopharm. Drug Dispos. 27: 371–386 (2006) .
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
P38α
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
GTR15264599 1 Vial
Lentiviral mouse Pfkp shRNA (UAS) - Lentiviral mouse Pfkp shRNA (UAS, RFP) (25)
Ask
View Details MBS6131494-01 0.1 mL
GLYCTK (Glycerate Kinase, CG9886-like, HBeAg-binding Protein 4, HBEBP4, HBeAgBP4A, HBEBP2, LP5910) (AP)
Ask
View Details MBS6131494-02 5x 0.1 mL
GLYCTK (Glycerate Kinase, CG9886-like, HBeAg-binding Protein 4, HBEBP4, HBeAgBP4A, HBEBP2, LP5910) (AP)
Ask
View Details 