URB524

URB524 is an irreversible FAAH inhibitor of O-aryl amino acid esters. URB524 inhibits FAAH by aminoformylation of Ser241. URB524 exhibits analgesic, antidepressant, and anti anxiety activity[1].

Product Specifications

CAS Number

[546141-07-5]

UNSPSC

12352005

Target

FAAH

Related Pathways

Metabolic Enzyme/Protease; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Smiles

O=C(NC1CCCCC1)OC2=CC=CC(C3=CC=CC=C3)=C2

Molecular Formula

C19H21NO2

Molecular Weight

295.38

References & Citations

[1]Lodola A, et al. Identification of productive inhibitor binding orientation in fatty acid amide hydrolase (FAAH) by QM/MM mechanistic modelling. Chem Commun (Camb) . 2008 Jan 14; (2) :214-6.