Glipentide

Glipentide is a sulfonylurea receptor agonist. Glipentide increases the concentration of fructose-2,6-bisphosphate in rat hepatocytes and inhibits basal gluconeogenesis. Glipentide can reduce glycerol production in rat adipose tissue. Glipentide can be used in research on endocrine and metabolic diseases such as diabetes[1][2].

Product Specifications

CAS Number

[32797-92-5]

UNSPSC

12352005

Hazard Statement

H317-H341-H361

Target

Others

Related Pathways

Others

Field of Research

Metabolic Disease

Smiles

O=C(C1=CC=CC=C1OC)NCCC2=CC=C(C=C2)S(=O)(NC(NC3CCCC3)=O)=O

Molecular Formula

C22H27N3O5S

Molecular Weight

445.53

Precautions

P261-P272-P280-P302+P352-P362+P364-P405-P501

References & Citations

[1]López-Alarcón L, et al. Glipentide and glucose metabolism in isolated rat hepatocytes. Biochem Pharmacol. 1988 Aug 15;37 (16) :3177-82.|[2]Herrera E. Effects of sulfonylureas (tolbutamide, glipentide and glibenclamide) on in vitro glycerol metabolism in adipose tissue from rats. Life Sci. 1975 Feb 15;16 (4) :645-50.