Tetrahydromagnolol
Tetrahydromagnolol (Magnolignan), the main metabolite of Magnolol, is a potent and selective cannabinoidCB2 receptor agonist (EC50 =170 nM) and GPR55 antagonist. The Ki of Tetrahydromagnolol for CB2 is 416 nM, 20-fold higher than for the CB1 receptor. Magnolol shows antifungal, anti-inflammatory and analgesic effects[1][2][3][4].
Product Specifications
CAS Number
20601-85-8
Product Name Alternative
Magnolignan
UNSPSC
12352005
Target
Cannabinoid Receptor; Drug Metabolite; GPR55
Related Pathways
GPCR/G Protein; Metabolic Enzyme/Protease; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Infection; Inflammation/Immunology; Neurological Disease
Purity
99.89
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
OC1=CC=C(CCC)C=C1C2=CC(CCC)=CC=C2O
Molecular Formula
C18H22O2
Molecular Weight
270.37
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
CB1; CB2
Available Sizes
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
Epoxide hydrolase (EPHX1) (NM_000120) Human Over-expression Lysate
