(R) -6-Hydroxybuspirone

(R) -6-Hydroxybuspirone is a metabolite of the anxiolytic agent Buspirone (HY-B1115A) . (R) -6-Hydroxybuspirone itself also has anxiolytic activity[1].

Product Specifications

CAS Number

[477930-30-6]

Product Name Alternative

BMS-442608

UNSPSC

12352005

Target

Drug Metabolite

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Neurological Disease

Smiles

O=C(CC1([C@@H](O)C2=O)CCCC1)N2CCCCN(CC3)CCN3C4=NC=CC=N4

Molecular Formula

C21H31N5O3

Molecular Weight

401.50

References & Citations

[1]Landwehr M, et al. Enantioselective α-hydroxylation of 2-arylacetic acid derivatives and buspirone catalyzed by engineered cytochrome P450 BM-3. Journal of the American Chemical Society. 2006 May 10;128 (18) :6058-9.