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RLX (hydrochloride)

RLX (PD 139530) hydrochloride is the hydrochloride of RLX (HY-116604) . RLX is a PI3K/Akt/FoxO3a signaling inhibitor, possessing significant therapeutic potential in experimental colon cancer. RLX can effectively modulate the tumor microenvironment, enhancing the efficacy of cancer immunotherapy. RLX demonstrates the ability to improve the retention time of therapeutic agents within the tumor microenvironment by utilizing advanced nanoparticle delivery systems. RLX can be integrated with various treatment modalities, such as chemotherapy and radiotherapy, to enhance overall tumor therapy effectiveness[1].

Product Specifications

CAS Number

[21314-60-3]

Product Name Alternative

PD 139530 (hydrochloride)

UNSPSC

12352005

Target

Akt; PI3K

Related Pathways

PI3K/Akt/mTOR

Field of Research

Cancer

Smiles

O=C1C2=C(N=C3N1CCCCC3)C=CC=C2.Cl

Molecular Formula

C13H15ClN2O

Molecular Weight

250.72

References & Citations

[1]Qazi AK, et al. Quinazoline based small molecule exerts potent tumour suppressive properties by inhibiting PI3K/Akt/FoxO3a signalling in experimental colon cancer. Cancer Lett. 2015 Apr 1;359 (1) :47-56.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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