L 858051 (dihydrochloride)
L 858051 dihydrochloride is an analog of Forskolin that activates adenylate cyclase while also having modulatory effects on intracellular cAMP levels, particularly enhancing the CNG current in cardiac myocytes[1].
Product Specifications
CAS Number
115116-37-5
Product Name Alternative
7DMB-Forskolin
UNSPSC
12352005
Target
Adenylate Cyclase
Related Pathways
GPCR/G Protein
Field of Research
Cardiovascular Disease
Smiles
O=C(O[C@H]1[C@@H](O)[C@@]2([H])C(C)(C)CC[C@H](O)[C@]2(C)[C@]3(O)[C@]1(C)O[C@@](C)(C=C)CC3=O)CCCN4CCN(C)CC4.Cl.Cl
Molecular Formula
C29H50Cl2N2O7
Molecular Weight
609.62
References & Citations
[1]Negative feedback exerted by cAMP-dependent protein kinase and cAMP phosphodiesterase on subsarcolemmal cAMP signals in intact cardiac myocytes: an in vivo study using adenovirus-mediated expression of CNG channels.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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