L 858051 (dihydrochloride)

L 858051 dihydrochloride is an analog of Forskolin (HY-15371) that activates adenylate cyclase while also having modulatory effects on intracellular cAMP levels, particularly enhancing the CNG current in cardiac myocytes[1].

Product Specifications

CAS Number

[115116-37-5]

Product Name Alternative

7DMB-Forskolin

UNSPSC

12352005

Target

Adenylate Cyclase

Related Pathways

GPCR/G Protein

Field of Research

Cardiovascular Disease

Smiles

O=C(O[C@H]1[C@@H](O)[C@@]2([H])C(C)(C)CC[C@H](O)[C@]2(C)[C@]3(O)[C@]1(C)O[C@@](C)(C=C)CC3=O)CCCN4CCN(C)CC4.Cl.Cl

Molecular Formula

C29H50Cl2N2O7

Molecular Weight

609.62

References & Citations

[1]Negative feedback exerted by cAMP-dependent protein kinase and cAMP phosphodiesterase on subsarcolemmal cAMP signals in intact cardiac myocytes: an in vivo study using adenovirus-mediated expression of CNG channels.