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Selenotifen

Selenotifen (BN 52256) is an antiallergic agent. Selenotifen is a highly potent antagonist to PAF receptors. Selenotifen exhibits a statistically significant antiarrhythmic effect[1][2].

Product Specifications

CAS Number

[135472-91-2]

Product Name Alternative

BN 52256

UNSPSC

12352005

Target

Platelet-activating Factor Receptor (PAFR)

Related Pathways

GPCR/G Protein

Field of Research

Inflammation/Immunology; Cardiovascular Disease

Smiles

O=C1C2=C(/C(C3=C(C1)C=CC=C3)=C4CCN(CC\4)C)C=C[Se]2

Molecular Formula

C19H19NOSe

Molecular Weight

356.32

References & Citations

[1]May SW, et al. Selenium-based antihypertensives. Rationale and potential. Drugs. 1998 Dec;56 (6) :959-64. |[2]Mest HJ, et al. Effect of BN 52256 and other mediator antagonists on ouabain-induced cardiac arrhythmia in a model of anaphylaxis in guinea-pigs. Pharmacol Res. 1992 Feb-Mar;25 (2) :173-80.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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