Selenotifen
Selenotifen (BN 52256) is an antiallergic agent. Selenotifen is a highly potent antagonist to PAF receptors. Selenotifen exhibits a statistically significant antiarrhythmic effect[1][2].
Product Specifications
CAS Number
135472-91-2
Product Name Alternative
BN 52256
UNSPSC
12352005
Target
Platelet-activating Factor Receptor (PAFR)
Related Pathways
GPCR/G Protein
Field of Research
Inflammation/Immunology; Cardiovascular Disease
Smiles
O=C1C2=C(/C(C3=C(C1)C=CC=C3)=C4CCN(CC\4)C)C=C[Se]2
Molecular Formula
C19H19NOSe
Molecular Weight
356.32
References & Citations
[1]May SW, et al. Selenium-based antihypertensives. Rationale and potential. Drugs. 1998 Dec;56 (6) :959-64. |[2]Mest HJ, et al. Effect of BN 52256 and other mediator antagonists on ouabain-induced cardiac arrhythmia in a model of anaphylaxis in guinea-pigs. Pharmacol Res. 1992 Feb-Mar;25 (2) :173-80.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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