AZT triphosphate (tetraammonium)
AZT triphosphate (3'-Azido-3'-deoxythymidine-5'-triphosphate) tetraammonium is an active triphosphate metabolite of Zidovudine (AZT) . AZT triphosphate tetraammonium exhibits antiretroviral activity and inhibits replication of HIV. AZT triphosphate tetraammonium also inhibits the DNA polymerase of HBV. AZT triphosphate tetraammonium activates the mitochondria-mediated apoptosis pathway[1][2][3].
Product Specifications
CAS Number
106060-92-8
Product Name Alternative
3'-Azido-3'-deoxythymidine-5'-triphosphate (tetraammonium)
UNSPSC
12352005
Target
Apoptosis; DNA/RNA Synthesis; HBV; HIV; Reactive Oxygen Species (ROS)
Related Pathways
Anti-infection; Apoptosis; Cell Cycle/DNA Damage; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Applications
COVID-19-anti-virus
Field of Research
Infection
Purity
99.25
Solubility
DMSO : 100 mg/mL (ultrasonic; warming; heat to 70°C)
Smiles
O=C1NC(N([C@@H](C[C@@H]2N=[N+]=[N-])O[C@@H]2COP(OP(O)(OP(O)(O)=O)=O)(O)=O)C=C1C)=O.N.N.N.N
Molecular Formula
C10H28N9O13P3
Molecular Weight
575.30
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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