(21R) -Argatroban

(21R) -Argatroban is a diastereoisomer of Argatroban (HY-B0375) . (21R) -Argatroban is also an inhibitor of thrombin with anticoagulant activity. (21R) -Argatroban can be used for research related to anticoagulation[1][2].

Product Specifications

CAS Number

[121785-71-5]

UNSPSC

12352005

Hazard Statement

H312-H319

Target

Thrombin

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Cardiovascular Disease

Smiles

O=C(N1[C@H](C[C@@H](CC1)C)C(O)=O)[C@H](CCCNC(N)=N)NS(=O)(C2=C3C(C[C@H](CN3)C)=CC=C2)=O

Molecular Formula

C23H36N6O5S

Molecular Weight

508.63

Precautions

P264-P280-P302+P352-P305+P351+P338-P363-P501

References & Citations

[1]Ferraboschi P, et al. Crystallographic, spectroscopic, and theoretical investigation of the efficiently separated 21R and 21S-diastereoisomers of argatroban. Chirality. 2013 Dec;25 (12) :871-82.|[2]Rawson TE, et al. Separation of 21- (R) - and 21- (S) -argatroban: solubility and activity of the individual diastereoisomers. J Pharm Sci. 1993 Jun;82 (6) :672-3.