(21R) -Argatroban
(21R) -Argatroban is a diastereoisomer of Argatroban (HY-B0375) . (21R) -Argatroban is also an inhibitor of thrombin with anticoagulant activity. (21R) -Argatroban can be used for research related to anticoagulation[1][2].
Product Specifications
UNSPSC
12352005
Hazard Statement
H312-H319
Target
Thrombin
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cardiovascular Disease
Smiles
O=C(N1[C@H](C[C@@H](CC1)C)C(O)=O)[C@H](CCCNC(N)=N)NS(=O)(C2=C3C(C[C@H](CN3)C)=CC=C2)=O
Molecular Formula
C23H36N6O5S
Molecular Weight
508.63
Precautions
P264-P280-P302+P352-P305+P351+P338-P363-P501
References & Citations
[1]Ferraboschi P, et al. Crystallographic, spectroscopic, and theoretical investigation of the efficiently separated 21R and 21S-diastereoisomers of argatroban. Chirality. 2013 Dec;25 (12) :871-82.|[2]Rawson TE, et al. Separation of 21- (R) - and 21- (S) -argatroban: solubility and activity of the individual diastereoisomers. J Pharm Sci. 1993 Jun;82 (6) :672-3.
Shipping Conditions
Room temperature
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-116363/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
CAS Number
[121785-71-5]
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