Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

5-Fluoro-2'-deoxycytidine (Standard)

5-Fluoro-2'-deoxycytidine (Standard) is the analytical standard of 5-Fluoro-2'-deoxycytidine. This product is intended for research and analytical applications. 5-Fluoro-2'-deoxycytidine (FdCyd), a fluoropyrimidine nucleoside analogue, is a DNA methyltransferase (DNMT) inhibitor. 5-Fluoro-2'-deoxycytidine is a tumor-selective proagent of thymidylate synthase inhibitor 5-fluoro-2′-dUMP. 5-Fluoro-2'-deoxycytidine can induce cell cycle arrest in tumor cells through the DNA damage response, and it has anti-tumor activity[1][2][3].

Product Specifications

CAS Number

10356-76-0

UNSPSC

12352100

Target

DNA Methyltransferase; Reference Standards

Related Pathways

Epigenetics; Others

Field of Research

Cancer

Smiles

O[C@H]1C[C@H](N2C(N=C(N)C(F)=C2)=O)O[C@@H]1CO

Molecular Formula

C9H12FN3O4

Molecular Weight

245.21

References & Citations

[1]Beumer JH, et, al. Pharmacokinetics, metabolism, and oral bioavailability of the DNA methyltransferase inhibitor 5-fluoro-2'-deoxycytidine in mice. Clin Cancer Res. 2006 Dec 15;12 (24) :7483-91.|[2]Osterman DG, et, al. 5-Fluorocytosine in DNA is a mechanism-based inhibitor of HhaI methylase. Biochemistry. 1988 Jul 12;27 (14) :5204-10.|[3]Zhao Q, et al. Inhibition of cancer cell proliferation by 5-fluoro-2'-deoxycytidine, a DNA methylation inhibitor, through activation of DNA damage response pathway. Springerplus. 2012 Dec;1 (1) :65.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Mouse Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 3 (ACAP3) ELISA Kit
MBS7232374-01 48 Well

Mouse Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 3 (ACAP3) ELISA Kit

Sign In for Pricing
View Details
Mouse Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 3 (ACAP3) ELISA Kit
MBS7232374-02 96 Well

Mouse Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 3 (ACAP3) ELISA Kit

Sign In for Pricing
View Details
Mouse Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 3 (ACAP3) ELISA Kit
MBS7232374-03 5x 96 Well

Mouse Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 3 (ACAP3) ELISA Kit

Sign In for Pricing
View Details
Mouse Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 3 (ACAP3) ELISA Kit
MBS7232374-04 10x 96 Well

Mouse Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 3 (ACAP3) ELISA Kit

Sign In for Pricing
View Details
C9orf30 Polyclonal Antibody, AbBy Fluor™ 555 Conjugated
bs-15326R-BF555 100 µL

C9orf30 Polyclonal Antibody, AbBy Fluor™ 555 Conjugated

Sign In for Pricing
View Details
5- ((2-Chlorophenoxy) methyl) furan-2-carboxylic acid
OR1055549-01 250 mg

5- ((2-Chlorophenoxy) methyl) furan-2-carboxylic acid

Sign In for Pricing
View Details