Lignarenone B

Lignarenone B is a phenyl conjugated trienone. Lignarenone B can be isolated from the Mediterranean bullomorph Scaphander lignarius. Lignarenone B can inhibit the activity of GSK3β. Lignarenone B can be used in the research of Alzheimer's disease[1][2].

Product Specifications

CAS Number

[125010-17-5]

UNSPSC

12352005

Target

GSK-3

Related Pathways

PI3K/Akt/mTOR; Stem Cell/Wnt

Field of Research

Neurological Disease

Smiles

CC(/C(C)=C/C=C/C=C/C1=CC=CC=C1)=O

Molecular Formula

C15H16O

Molecular Weight

212.29

References & Citations

[1]Llorach-Pares L, et al. Meridianins and Lignarenone B as Potential GSK3β Inhibitors and Inductors of Structural Neuronal Plasticity. Biomolecules. 2020 Apr 21;10 (4) :639. |[2]Alvarez R, et al. Stereocontrolled Synthesis of Polyenic Ketones from Marine Opisthobranchs[J]. Natural Product Letters, 1995, 6 (2) : 127-132.