Lignarenone B
Lignarenone B is a phenyl conjugated trienone. Lignarenone B can be isolated from the Mediterranean bullomorph Scaphander lignarius. Lignarenone B can inhibit the activity of GSK3β. Lignarenone B can be used in the research of Alzheimer's disease[1][2].
Product Specifications
CAS Number
125010-17-5
UNSPSC
12352005
Target
GSK-3
Related Pathways
PI3K/Akt/mTOR; Stem Cell/Wnt
Field of Research
Neurological Disease
Smiles
CC(/C(C)=C/C=C/C=C/C1=CC=CC=C1)=O
Molecular Formula
C15H16O
Molecular Weight
212.29
References & Citations
[1]Llorach-Pares L, et al. Meridianins and Lignarenone B as Potential GSK3β Inhibitors and Inductors of Structural Neuronal Plasticity. Biomolecules. 2020 Apr 21;10 (4) :639. |[2]Alvarez R, et al. Stereocontrolled Synthesis of Polyenic Ketones from Marine Opisthobranchs[J]. Natural Product Letters, 1995, 6 (2) : 127-132.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
GSK-3β
Frequently Asked Questions
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