LY-326188
LY-326188 is a HIV-1 protease inhibitor, with an IC50 of 0.42 nM. LY326188 exhibits potent protection of HIV-1 infected cells[1].
Product Specifications
CAS Number
[169168-35-8]
UNSPSC
12352005
Target
HIV; HIV Protease
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Field of Research
Infection
Smiles
O=C(N[C@@H](CSC1=CC=CC=C1)[C@@H](CN2[C@@H](C[C@]3([C@@]([H])(C2)CCS3)[H])C(NC(C)(C)C)=O)O)O[C@@H]([C@H]4C(C)C)CCS4(=O)=O
Molecular Formula
C30H47N3O6S3
Molecular Weight
641.91
References & Citations
[1]Hornback W J, et al. Synthesis and pharmacokinetics of potent carbamate HIV-1 protease inhibitors containing novel high affinity hydroxyethylamine isosteres[J]. Bioorganic & Medicinal Chemistry Letters, 1995, 5 (23) : 2891-2896.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
HIV-1
Curated Selection
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