Nimbolide (Standard)
Nimbolide (Standard) is the analytical standard of Nimbolide. This product is intended for research and analytical applications. Nimbolide is a triterpene compound that can be isolated from neem (Azadirachta indica), possesses anticancer and antiproliferative activity. Nimbolide induces tumor cell apoptosis by inhibiting NF-κB and CDK4/CDK6 kinase. Nimbolide suppresses the Wnt, PI3K-Akt, MAPK and JAK-STAT signaling pathways[1][2].
Product Specifications
CAS Number
25990-37-8
UNSPSC
12352100
Target
Apoptosis; CDK; NF-κB; Reference Standards; Wnt
Related Pathways
Apoptosis; Cell Cycle/DNA Damage; NF-κB; Others; Stem Cell/Wnt
Field of Research
Cancer
Smiles
C[C@]12[C@@]3([H])[C@](OC([C@@]3(C=CC2=O)C)=O)([H])[C@]4([H])[C@]([C@@H]1CC(OC)=O)(C5=C(C)[C@@](C6=COC=C6)([H])C[C@@]5([H])O4)C
Molecular Formula
C27H30O7
Molecular Weight
466.52
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Frequently Asked Questions
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