(rac) -K20
(rac) -K20 is the racemate of K20, a KRas G12C inhibitor with an IC50 of 1.16 μM. K20 has antitumor activity[1].
Product Specifications
CAS Number
[2915618-92-5]
UNSPSC
12352005
Target
Others
Related Pathways
Others
Field of Research
Cancer
Smiles
C=C(C(N1CCN(C(C1)C)C2=NC=NC3=C(C(C4=CC(Cl)=CC=C4OC)=C(C=C23)Cl)F)=O)C(F)(F)F
Molecular Formula
C24H20Cl2F4N4O2
Molecular Weight
543.34
References & Citations
[1]Zhao H, et al. Discovery of ARS-1620 analogs as KRas G12C inhibitors with high in vivo antitumor activity. Bioorg Chem. 2022 Apr;121:105652.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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