(rac) -K20
(rac) -K20 is the racemate of K20, a KRas G12C inhibitor with an IC50 of 1.16 μM. K20 has antitumor activity[1].
Product Specifications
CAS Number
2915618-92-5
UNSPSC
12352005
Target
Others
Related Pathways
Others
Field of Research
Cancer
Smiles
C=C(C(N1CCN(C(C1)C)C2=NC=NC3=C(C(C4=CC(Cl)=CC=C4OC)=C(C=C23)Cl)F)=O)C(F)(F)F
Molecular Formula
C24H20Cl2F4N4O2
Molecular Weight
543.34
References & Citations
[1]Zhao H, et al. Discovery of ARS-1620 analogs as KRas G12C inhibitors with high in vivo antitumor activity. Bioorg Chem. 2022 Apr;121:105652.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
RG232376 10 µg
TROY (TNFRSF19) (NM_001204459) Human Tagged ORF Clone
Sign In for Pricing
View Details EIA07629Gu 1 Kit
Guinea pig Granulocyte Chemotactic Protein-2 (GCP-2) ELISA Kit
Sign In for Pricing
View Details 