Anabaseine-d4
Anabaseine-d4 is the deuterium labeled Anabaseine. Anabaseine is a non-selective nicotinic agonist. Anabaseine stimulates all AChRs, preferentially stimulates skeletal muscle and brain α7 subtypes[1][2]. Anabaseine is also a weak partial agonist at α4β2 nAChRs[3].
Product Specifications
CAS Number
1020719-05-4
UNSPSC
12352005
Target
Isotope-Labeled Compounds; nAChR
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling; Others
Field of Research
Neurological Disease
Smiles
[2H]C1=C([2H])N=C([2H])C(C2=NCCCC2)=C1[2H]
Molecular Formula
C10H8D4N2
Molecular Weight
164.24
References & Citations
[1]Kem W, et al. The Nemertine Toxin Anabaseine and Its Derivative DMXBA (GTS-21) : Chemical and Pharmacological Properties. Mar Drugs. 2006;4 (3) :255-273.|[2]Summers KL et al. Nicotinic agonist modulation of neurotransmitter levels in the rat frontoparietal cortex. Jpn J Pharmacol. 1997 Jun;74 (2) :139-46.|[3]Andrud K, et al. Investigation of the Possible Pharmacologically Active Forms of the Nicotinic Acetylcholine Receptor Agonist Anabaseine. Mar Drugs. 2019;17 (11) :614. Published 2019 Oct 29.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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