Anabaseine (Standard)

Anabaseine (Standard) is the analytical standard of Anabaseine. This product is intended for research and analytical applications. Anabaseine is a non-selective nicotinic agonist. Anabaseine stimulates all AChRs, preferentially stimulates skeletal muscle and brain α7 subtypes[1][2]. Anabaseine is also a weak partial agonist at α4β2 nAChRs[3].

Product Specifications

CAS Number

[3471-05-4]

UNSPSC

12352100

Target

NAChR; Reference Standards

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling; Others

Field of Research

Neurological Disease

Smiles

C1(C2=CC=CN=C2)=NCCCC1

Molecular Formula

C10H12N2

Molecular Weight

160.22

References & Citations

[1]Kem W, et al. The Nemertine Toxin Anabaseine and Its Derivative DMXBA (GTS-21) : Chemical and Pharmacological Properties. Mar Drugs. 2006;4 (3) :255-273.|[2]Summers KL et al. Nicotinic agonist modulation of neurotransmitter levels in the rat frontoparietal cortex. Jpn J Pharmacol. 1997 Jun;74 (2) :139-46.|[3]Andrud K, et al. Investigation of the Possible Pharmacologically Active Forms of the Nicotinic Acetylcholine Receptor Agonist Anabaseine. Mar Drugs. 2019;17 (11) :614. Published 2019 Oct 29.