Xanthosine-5'-Triphosphate (trisodium)

Xanthosine-5'-Triphosphate (5'-XTP) trisodium, a nucleotide, is produced by deamination of purine bases. Xanthosine-5'-Triphosphate trisodium is a substrate of inosine triphosphate pyrophosphatase (ITPase) [1][2].

Product Specifications

CAS Number

[105931-36-0]

Product Name Alternative

5'-XTP (trisodium)

UNSPSC

12352005

Target

DNA/RNA Synthesis; Nucleoside Antimetabolite/Analog; Phosphatase

Related Pathways

Cell Cycle/DNA Damage; Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Others

Concentration

100 mM * 100 μL in Water

Purity

99.26

Smiles

O=C(C(N=C1)=C(N2)N1[C@@H]3O[C@H](COP(OP(OP(O)(O[Na])=O)(O[Na])=O)(O[Na])=O)[C@@H](O)[C@H]3O)NC2=O

Molecular Formula

C10H12N4Na3O15P3

Molecular Weight

590.11

References & Citations

[1]Lin S, et al. Cloning, expression, and characterization of a human inosine triphosphate pyrophosphatase encoded by the itpa gene. J Biol Chem. 2001 Jun 1;276 (22) :18695-701.|[2]Davies O, et, al. Characterisation of multiple substrate-specific (d) ITP/ (d) XTPase and modelling of deaminated purine nucleotide metabolism. BMB Rep. 2012 Apr;45 (4) :259-64.