ML175
ML175 is a specific glutathione transferase Omega 1-1 (GSTO1-1) inhibitor. ML175 can significantly activate Akt and MEK1/2 kinases. ML175 can be used in the research of diseases such as Parkinson's disease[1].
Product Specifications
CAS Number
[610263-01-9]
UNSPSC
12352005
Target
Akt; Glutathione S-transferase; MEK
Related Pathways
MAPK/ERK Pathway; Metabolic Enzyme/Protease; PI3K/Akt/mTOR
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Neurological Disease
Smiles
O=C(NCCCN(C(CCl)=O)C1=CC=C([N+]([O-])=O)C=C1)C(F)(F)F
Molecular Formula
C13H13ClF3N3O4
Molecular Weight
367.71
References & Citations
[1]Saisawang C, et al. Glutathione transferase Omega 1-1 (GSTO1-1) modulates Akt and MEK1/2 signaling in human neuroblastoma cell SH-SY5Y. Proteins. 2019 Jul;87 (7) :588-595.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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