Dorrigocin A
Dorrigocin A is an analog of Migrastatin (HY-121452) . Dorrigocin A can inhibit the carboxymethyltransferase involved in Ras processing and reverse the morphology of ras-transformed NIH/3T3 cells. Dorrigocin A is promising for research of anti-cancer and anti-arthritis agents[1].
Product Specifications
CAS Number
[158446-29-8]
UNSPSC
12352005
Target
Ras
Related Pathways
GPCR/G Protein; MAPK/ERK Pathway
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Smiles
O=C(O)/C=C/CC/C=C/[C@H](OC)[C@@H](O)[C@H](C)/C=C(C)/[C@H](O)[C@H](C)C(CCCC(C1)CC(NC1=O)=O)=O
Molecular Formula
C27H41NO8
Molecular Weight
507.62
References & Citations
[1]Anquetin G, et al. Synthesis of novel migrastatin and dorrigocin A analogues from D-glucal. Chemistry. 2008;14 (5) :1592-600.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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