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PyP-1

PyP-1 is a highly selective and potent PDE10 inhibitor. PyP-1 has a strong inhibitory effect on human PDE10A2 enzyme (Ki = 0.32 nM) . PyP-1 can improve cognitive behavior. PyP-1 commonly used in research on conditions such as schizophrenia and cognitive impairment[1].

Product Specifications

CAS Number

[1370527-16-4]

UNSPSC

12352005

Target

Phosphodiesterase (PDE)

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Neurological Disease

Smiles

CN1N=CC(CNC2=CC(OC[C@@H]3[C@@H](C4=NC=CC=C4)C3)=NC5=CC=NN25)=C1

Molecular Formula

C20H21N7O

Molecular Weight

375.43

References & Citations

[1]Christopher D. Cox, et al. Pyrazolopyrimidine pde 10 inhibitors. US8957077 B2.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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