6-MOMIPP
6-MOMIPP is a brain-penetrant microtubule disruptor that targets the colchicine site on β-tubulin. 6-MOMIPP can induce mitotic arrest and cell apoptosis. 6-MOMIPP has broad activity against the viability of multiple glioblastoma, melanoma and lung carcinoma cell lines. 6-MOMIPP can be used for the research of cancer[1].
Product Specifications
CAS Number
[1961272-45-6]
UNSPSC
12352005
Target
Apoptosis; Microtubule/Tubulin
Related Pathways
Apoptosis; Cell Cycle/DNA Damage; Cytoskeleton
Field of Research
Cancer
Smiles
O=C(C1=CC=NC=C1)/C=C/C2=C(C)NC3=C2C=CC(OC)=C3
Molecular Formula
C18H16N2O2
Molecular Weight
292.33
References & Citations
[1]Du S, et al. 6-MOMIPP, a novel brain-penetrant anti-mitotic indolyl-chalcone, inhibits glioblastoma growth and viability. Cancer Chemother Pharmacol. 2019 Feb;83 (2) :237-254.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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