Neamine (tetrahydrochloride)

Neamine tetrahydrochloride, a degradation product of Neomycin, is a broad-spectrum aminoglycoside antibiotic. Neamine tetrahydrochloride is an anti-angiogenesis agent targeting angiogenin. Neamine tetrahydrochloride has potent antibacterial, antitumor and neuroprotective activities[1][2].

Product Specifications

CAS Number

[15446-43-2]

UNSPSC

12352005

Target

Antibiotic; Bacterial

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Infection; Neurological Disease

Purity

99.92

Solubility

10 mM in DMSO

Smiles

O[C@H]([C@H]([C@@H](C[C@@H]1N)N)O)[C@@H]1O[C@H]2O[C@@H]([C@H]([C@@H]([C@H]2N)O)O)CN.Cl.Cl.Cl.Cl

Molecular Formula

C12H30Cl4N4O6

Molecular Weight

468.20

References & Citations

[1]Ya-Ping Liu, et al. Neamine Inhibits Growth of Pancreatic Cancer Cells in Vitro and in Vivo. J Huazhong Univ Sci Technolog Med Sci. 2016 Feb;36 (1) :82-87.|[2]R Ning, et al. Neamine Induces Neuroprotection After Acute Ischemic Stroke in Type One Diabetic Rats. Neuroscience. 2014 Jan 17;257:76-85.