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(R) -Eslicarbazepine acetate

(R) -Eslicarbazepine acetate (BIA 2-059) is the R-enantiomer of Eslicarbazepine acetate. Eslicarbazepine acetate is an antiepileptic agent, is a dual a dual Inhibitor of β-Secretase and voltage-gated sodium channel[1][2].

Product Specifications

CAS Number

186694-45-1

Product Name Alternative

BIA 2-059; (R) -Licarbazepine acetate

UNSPSC

12352005

Target

Beta-secretase; Sodium Channel

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Field of Research

Neurological Disease

Smiles

CC(O[C@H]1C2=CC=CC=C2N(C3=CC=CC=C3C1)C(N)=O)=O

Molecular Formula

C17H16N2O3

Molecular Weight

296.32

References & Citations

[1]Shaikh S, et, al. Aptiom (eslicarbazepine acetate) as a dual inhibitor of β-secretase and voltage-gated sodium channel: advancement in Alzheimer's disease-epilepsy linkage via an enzoinformatics study. CNS Neurol Disord Drug Targets. 2014;13 (7) :1258-62.|[2]Alves G, et, al. Stereoselective disposition of S- and R-licarbazepine in mice. Chirality. 2008 Jun;20 (6) :796-804.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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