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Didesmethylpromazine

Didesmethylpromazine (Compound 18) is a trypanothione reductase inhibitor with an I50of 1412 μM against T. cruzi trypanothione reductase. Didesmethylpromazine can be used in the research of trypanosome and leishmania infections[1].

Product Specifications

CAS Number

[2095-21-8]

UNSPSC

12352005

Hazard Statement

H315-H319-H320

Target

Parasite

Related Pathways

Anti-infection

Field of Research

Infection

Smiles

S1C=2C=CC=CC2N(C=3C=CC=CC13)CCCN

Molecular Formula

C15H16N2S

Molecular Weight

256.37

Precautions

P264-P280-P302+P352-P305+P351+P338-P362

References & Citations

[1]Chan C, et al. Phenothiazine inhibitors of trypanothione reductase as potential antitrypanosomal and antileishmanial drugs. J Med Chem. 1998 Jan 15;41 (2) :148-56.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

Leishmania; Trypanosoma

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