Nooglutil
Nooglutil (Nooglutyl; ONK-10) is a positive modulator of AMPA-type glutamate receptors (AMPARs) . Nooglutil also regulates dopamine D2 receptor function to exert anxiolytic effects. Nooglutil is promising for research of neurodegenerative disorders (e.g., Alzheimer’s disease) [1].
Product Specifications
Product Name Alternative
Nooglutyl; ONK-10
UNSPSC
12352005
Target
Dopamine Receptor; iGluR
Related Pathways
GPCR/G Protein; Membrane Transporter/Ion Channel; Neuronal Signaling
Field of Research
Neurological Disease
Smiles
O=C(O)CC[C@@H](C(O)=O)NC(C1=CC(O)=CN=C1)=O
Molecular Formula
C11H12N2O6
Molecular Weight
268.22
References & Citations
[1]Voronina TA, et al. Effect of nooglutil on benzodiazepine withdrawal syndrome and binding of 3H-spiperone with D2 receptors in rat striatum. Bull Exp Biol Med. 2002 Nov;134 (5) :448-50.
Shipping Conditions
Room temperature
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-114576/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
D2 Receptor
CAS Number
[112193-35-8]
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