Nooglutil

Nooglutil (Nooglutyl; ONK-10) is a positive modulator of AMPA-type glutamate receptors (AMPARs) . Nooglutil also regulates dopamine D2 receptor function to exert anxiolytic effects. Nooglutil is promising for research of neurodegenerative disorders (e.g., Alzheimer’s disease) [1].

Product Specifications

CAS Number

[112193-35-8]

Product Name Alternative

Nooglutyl; ONK-10

UNSPSC

12352005

Target

Dopamine Receptor; iGluR

Related Pathways

GPCR/G Protein; Membrane Transporter/Ion Channel; Neuronal Signaling

Field of Research

Neurological Disease

Smiles

O=C(O)CC[C@@H](C(O)=O)NC(C1=CC(O)=CN=C1)=O

Molecular Formula

C11H12N2O6

Molecular Weight

268.22

References & Citations

[1]Voronina TA, et al. Effect of nooglutil on benzodiazepine withdrawal syndrome and binding of 3H-spiperone with D2 receptors in rat striatum. Bull Exp Biol Med. 2002 Nov;134 (5) :448-50.